Across TCGA pan-cancer cohorts, RHOBTB1 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RHOBTB1 data layer compared with 22 for mass-spec protein and 5 for mutation status.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RHOBTB1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RHOBTB1 expression acts as an unfavorable survival marker.
LUAD are the cancer types where RHOBTB1 mass-spec protein most reproducibly stratifies survival.