RHOB

Across TCGA cell cohorts, RHOB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,391 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHOB-associated GO terms across cancer lineages are Endothelial tube morphogenesis, Regulation of modification of postsynaptic structure, and Morphogenesis of an endothelium. Each is linked with RHOB in more than 13 cancer types. Because this analysis shows association rather than direction, both RHOB-to-partner and partner-to-RHOB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial tube morphogenesis grouped by RHOB-low versus RHOB-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOB→partner) and Y-score (partner→RHOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Endothelial tube morphogenesis →	+0.151	+2.446	.004	.008	1	14
BONE	Regulation of modification of postsynaptic structure →	+0.150	+2.025	<.001	.001	2	13
BLOOD_Myeloma	Morphogenesis of an endothelium →	+0.151	+2.446	.004	.008	1	14
UPPER_AERODIGESTIVE_TRACT	Response to hydrogen peroxide →	+0.104	+2.002	<.001	<.001	3	11
URINARY_TRACT	Regulation of modification of synaptic structure →	+0.100	+1.738	.002	.004	2	11
UPPER_AERODIGESTIVE_TRACT	Cellular response to epidermal growth factor stimulus →	+0.104	+1.582	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,391 associations by consensus.

Endothelial tube morphogenesis by RHOB expression — BLOOD_Myeloma

Explore this box plot interactively →