RHO

Across TCGA pan-cancer cohorts, RHO Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated RHO data layer compared with 24 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RHO Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RHO expression acts as an unfavorable survival marker.

BRCA, UCEC, and PRAD are the cancer types where RHO Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.500	0.963	<.001	34	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LIHC	DFS	Median	II,III,IV	0.020	0.427	<.001	6	view →
LUAD	OS	Median	All	0.176	0.670	.039	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

RHO–BRCA (OS)

Open the BRCA breakdown →