Across TCGA patient cohorts, RHD RNA expression is significantly associated with the go_rna of many other GO terms, with 7,088 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RHD-associated GO terms across cancer lineages are Positive regulation of DNA recombination, Obsolete histone modification, and TORC1 signaling. Each is linked with RHD in more than 29 cancer types. Because this analysis shows association rather than direction, both RHD-to-partner and partner-to-RHD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHD→partner) and Y-score (partner→RHD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of DNA recombination →	+0.071	+0.575	<.001	<.001	3	30
SCLC	Obsolete histone modification →	+0.124	+0.913	<.001	<.001	3	29
SCLC	TORC1 signaling →	+0.081	+0.768	<.001	<.001	3	29
SCLC	Autophagosome maturation →	+0.109	+1.026	<.001	<.001	3	28
SCLC	Nuclear-transcribed mRNA poly(A) tail shortening →	+0.101	+0.702	<.001	<.001	3	28
SCLC	Positive regulation of DNA metabolic process →	+0.058	+0.646	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,088 associations by consensus.

Exploration

RHD survival (RNA) · tumor vs normal (RNA) · all RHD data types