Across TCGA cell cohorts, RHD RNA expression is significantly associated with the go_rna of many other GO terms, with 3,093 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHD-associated GO terms across cancer lineages are Cytosolic transport, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with RHD in more than 12 cancer types. Because this analysis shows association rather than direction, both RHD-to-partner and partner-to-RHD results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHD→partner) and Y-score (partner→RHD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cytosolic transport →	+0.084	+0.263	<.001	<.001	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.192	+0.238	<.001	.001	3	13
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.188	+0.238	<.001	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.073	+0.167	<.001	<.001	3	13
BLOOD_Leukemia	Positive regulation of protein localization to mitochondrion →	+0.102	+1.095	<.001	.002	3	12
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.157	+0.228	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,093 associations by consensus.

Exploration

RHD survival (RNA) · tumor vs normal (RNA) · all RHD data types