RHCG

Across TCGA cell cohorts, RHCG mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RHCG-associated genes across cancer lineages are UCMA, OR10W1, and ELOA3DP. Each is linked with RHCG in more than 1 cancer types. Because this analysis shows association rather than direction, both RHCG-to-partner and partner-to-RHCG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UCMA grouped by RHCG-low versus RHCG-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHCG→partner) and Y-score (partner→RHCG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	UCMA →	+0.028	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	OR10W1 →	+0.016	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	ELOA3DP →	+0.044	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

UCMA by RHCG expression — LARGE_INTESTINE

Explore this box plot interactively →