Across TCGA pan-cancer cohorts, RHCE Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated RHCE data layer compared with 16 for mass-spec protein.
The strongest signal is observed in sarcoma (SARC), where higher RHCE Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RHCE expression acts as an unfavorable survival marker.
SARC, LGG, and SCLC are the cancer types where RHCE Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.