RHBG

Across TCGA pan-cancer cohorts, RHBG Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated RHBG data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RHBG Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated RHBG expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCEC show a favorable association.

DLBC, ESCA, and BLCA are the cancer types where RHBG Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	All	0.053	0.936	<.001	12	view →
ESCA	OS	Median	All	0.022	0.701	<.001	12	view →
BLCA	DFS	Median	All	1.000	0.325	.022	9	view →
LUSC	OS	Median	All	0.287	0.663	.012	6	view →
SKCM	DFS	Median	IV	0.040	0.454	.028	6	view →
UCEC	DFS	Median	All	1.000	0.831	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

RHBG–DLBC (OS)

Open the DLBC breakdown →