RHBDL3

Across TCGA patient cohorts, RHBDL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,144 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RHBDL3-associated proteins across cancer lineages are HDGFL3, CASP4, and EIF2S2. Each is linked with RHBDL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both RHBDL3-to-partner and partner-to-RHBDL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHBDL3 versus HDGFL3 in CCRCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDL3→partner) and Y-score (partner→RHBDL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	HDGFL3 →	+0.542	+0.148	<.001	<.001	3	6
HNSC	CASP4 →	-0.725	-0.834	<.001	<.001	3	5
GBM	EIF2S2 →	-0.167	-0.914	.006	.005	3	5
GBM	SARM1 →	+0.301	+0.898	<.001	<.001	3	4
GBM	STXBP1 →	+0.730	+1.105	<.001	<.001	3	4
GBM	STXBP2 →	-0.399	-1.007	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,144 associations by consensus.

RHBDL3 vs HDGFL3 — CCRCC

Explore this scatter interactively →