RHBDL2

Across TCGA cell cohorts, RHBDL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,086 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RHBDL2-associated GO terms across cancer lineages are Cell-substrate junction assembly, Protein localization to plasma membrane, and Regulation of antigen processing and presentation. Each is linked with RHBDL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both RHBDL2-to-partner and partner-to-RHBDL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction assembly grouped by RHBDL2-low versus RHBDL2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDL2→partner) and Y-score (partner→RHBDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cell-substrate junction assembly →	+0.181	+2.291	.002	<.001	3	12
BONE	Protein localization to plasma membrane →	+0.080	+1.142	<.001	<.001	3	12
PANCREAS	Regulation of antigen processing and presentation →	+0.211	+1.714	<.001	.004	3	12
PANCREAS	Regulation of potassium ion import →	+0.237	+2.831	<.001	<.001	3	12
URINARY_TRACT	Negative regulation of actin filament polymerization →	+0.207	+2.957	<.001	<.001	3	12
URINARY_TRACT	Negative regulation of supramolecular fiber organization →	+0.108	+2.358	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,086 associations by consensus.

Cell-substrate junction assembly by RHBDL2 expression — PANCREAS

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