RHBDF2

Across TCGA patient cohorts, RHBDF2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,257 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RHBDF2-associated genes across cancer lineages are SPATA6, ZNF491, and SLC2A13. Each is linked with RHBDF2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RHBDF2-to-partner and partner-to-RHBDF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHBDF2 versus SPATA6 in HNSC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDF2→partner) and Y-score (partner→RHBDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SPATA6 →	-0.714	-0.331	<.001	.002	3	6
GBM	ZNF491 →	-0.481	-0.449	<.001	<.001	3	5
BRCA	SLC2A13 →	-0.732	-0.400	<.001	.003	3	5
OV	ZNF738 →	-0.856	-0.444	<.001	.002	3	5
HNSC	ZFP28 →	-0.832	-0.317	<.001	.003	3	5
GBM	ZNF84 →	-0.663	-0.749	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,257 associations by consensus.

RHBDF2 vs SPATA6 — HNSC

Explore this scatter interactively →