RHBDF2

Across TCGA cell cohorts, RHBDF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,341 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHBDF2-associated GO terms across cancer lineages are Regulation of inflammatory response to antigenic stimulus, Cellular response to epidermal growth factor stimulus, and Positive regulation of intracellular protein transport. Each is linked with RHBDF2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RHBDF2-to-partner and partner-to-RHBDF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of inflammatory response to antigenic stimulus grouped by RHBDF2-low versus RHBDF2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDF2→partner) and Y-score (partner→RHBDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of inflammatory response to antigenic stimulus →	+0.145	+1.368	.001	.003	3	11
LUNG_NSCLC_LUSC	Cellular response to epidermal growth factor stimulus →	+0.122	+1.337	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Positive regulation of intracellular protein transport →	+0.068	+1.032	<.001	<.001	3	11
LUNG_SCLC	MHC class I protein complex assembly →	+0.098	+1.459	.007	.001	3	11
LUNG_SCLC	Peptide antigen assembly with MHC class I protein complex →	+0.098	+1.459	.007	.001	3	11
BREAST	Viral process →	+0.088	+1.032	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,341 associations by consensus.

Regulation of inflammatory response to antigenic stimulus by RHBDF2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →