RHBDF2

Across TCGA cell cohorts, RHBDF2 mutation is significantly associated with the RNA expression of many other genes, with 371 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHBDF2-associated genes across cancer lineages are GLTP, NABP2, and ZP1. Each is linked with RHBDF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBDF2-to-partner and partner-to-RHBDF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GLTP grouped by RHBDF2-low versus RHBDF2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDF2→partner) and Y-score (partner→RHBDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GLTP →	+0.749	+3.214	<.001	.006	3	2
BLOOD_Leukemia	NABP2 →	+0.681	+3.259	.001	.006	3	2
BLOOD_Leukemia	ZP1 →	+0.666	+3.376	.001	.006	3	2
BLOOD_Leukemia	CNPY2 →	+0.462	+3.259	.004	.006	3	2
CNS	DEFB133 →	+0.046	+6.357	<.001	<.001	3	1
BLOOD_Leukemia	IFT52 →	+0.511	+3.176	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 371 associations by consensus.

GLTP by RHBDF2 expression — BLOOD_Leukemia

Explore this box plot interactively →