RHBDF1

Across TCGA pan-cancer cohorts, RHBDF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RHBDF1 data layer compared with 25 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RHBDF1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RHBDF1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, LSCC, and LUAD are the cancer types where RHBDF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.663	0.273	<.001	87	view →
LSCC	DFS	Median	II,III,IV	0.512	0.863	<.001	60	view →
LUAD	OS	Median	III,IV	0.743	0.481	.031	3	view →
CCRCC	DFS	Median	All	0.867	0.736	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RHBDF1–PDAC (OS)

Open the PDAC breakdown →