RHBDF1

Across TCGA cell cohorts, RHBDF1 mutation is significantly associated with the RNA expression of many other genes, with 724 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHBDF1-associated genes across cancer lineages are HOXA1, AKAP3, and OSCP1. Each is linked with RHBDF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBDF1-to-partner and partner-to-RHBDF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXA1 grouped by RHBDF1-low versus RHBDF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDF1→partner) and Y-score (partner→RHBDF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HOXA1 →	-1.054	-3.169	.001	.009	3	2
LARGE_INTESTINE	AKAP3 →	+0.656	+3.364	.008	.002	3	2
BLOOD_Leukemia	OSCP1 →	+0.945	+3.789	<.001	<.001	3	2
LARGE_INTESTINE	BBOF1 →	+0.791	+3.169	.001	.009	3	2
LARGE_INTESTINE	ALDH6A1 →	+0.917	+3.064	.002	.009	3	2
LARGE_INTESTINE	FAM124A →	+0.737	+3.364	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 724 associations by consensus.

HOXA1 by RHBDF1 expression — LARGE_INTESTINE

Explore this box plot interactively →