RHBDD3

Across TCGA cell cohorts, RHBDD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,590 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RHBDD3-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Negative regulation of chromosome condensation, and Symbiont-mediated disruption of host cellular anatomical structure. Each is linked with RHBDD3 in more than 15 cancer types. Because this analysis shows association rather than direction, both RHBDD3-to-partner and partner-to-RHBDD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T-helper 17 cell lineage commitment grouped by RHBDD3-low versus RHBDD3-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDD3→partner) and Y-score (partner→RHBDD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of T-helper 17 cell lineage commitment →	+0.228	+1.542	.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.169	+0.780	<.001	.005	2	16
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.145	+1.189	.001	<.001	3	15
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.145	+1.189	.001	<.001	3	15
BONE	Microtubule nucleation →	+0.168	+1.463	<.001	<.001	3	13
BONE	DNA double-strand break processing involved in repair via single-strand annealing →	+0.077	+1.059	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,590 associations by consensus.

Positive regulation of T-helper 17 cell lineage commitment by RHBDD3 expression — OESOPHAGUS

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