RHBDD2

Across TCGA patient cohorts, RHBDD2 mutation is significantly associated with the RNA expression of many other genes, with 1,315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHBDD2-associated genes across cancer lineages are RN7SL266P, DIP2A, and GHITM. Each is linked with RHBDD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBDD2-to-partner and partner-to-RHBDD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL266P grouped by RHBDD2-low versus RHBDD2-high in GBM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDD2→partner) and Y-score (partner→RHBDD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RN7SL266P →	+0.227	+5.352	<.001	.005	3	2
UCEC	DIP2A →	+0.445	+3.467	.001	.002	3	2
UCEC	GHITM →	+0.723	+3.000	<.001	.001	3	2
UCEC	ZMYND19 →	+0.424	+4.119	.002	<.001	3	2
UCEC	ADAL →	+0.528	+2.332	.002	.003	3	2
UCEC	CKAP2L →	+0.790	+2.332	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,315 associations by consensus.

RN7SL266P by RHBDD2 expression — GBM

Explore this box plot interactively →