RHBDD2

Across TCGA patient cohorts, RHBDD2 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHBDD2-associated genes across cancer lineages are eEF2, GAPDH, and MEK1. Each is linked with RHBDD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RHBDD2-to-partner and partner-to-RHBDD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by RHBDD2-low versus RHBDD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDD2→partner) and Y-score (partner→RHBDD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.511	+2.000	.001	.032	3	1
UCEC	GAPDH →	+0.520	+2.321	.031	.034	3	1
UCEC	MEK1 →	+0.527	+3.584	.001	.002	3	1
UCEC	MSH2 →	-0.349	-2.973	<.001	.035	3	1
UCEC	p62 Lck ligand →	+0.504	+2.321	<.001	.033	3	1
UCEC	PCNA →	+0.312	+3.321	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

eEF2 by RHBDD2 expression — UCEC

Explore this box plot interactively →