RHBDD1

Across TCGA patient cohorts, RHBDD1 mutation is significantly associated with the RNA expression of many other genes, with 1,426 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHBDD1-associated genes across cancer lineages are NOP10, C19orf71, and VPS33B. Each is linked with RHBDD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBDD1-to-partner and partner-to-RHBDD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NOP10 grouped by RHBDD1-low versus RHBDD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDD1→partner) and Y-score (partner→RHBDD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NOP10 →	+0.479	+3.516	.002	.002	3	2
UCEC	C19orf71 →	+0.757	+3.595	<.001	.001	3	2
UCEC	VPS33B →	+0.322	+3.227	.008	.009	3	2
UCEC	DYNC1H1 →	+0.535	+2.818	.001	.001	3	2
UCEC	SAMM50 →	+0.476	+3.475	.009	.002	3	2
UCEC	CLCN7 →	+0.534	+3.501	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,426 associations by consensus.

NOP10 by RHBDD1 expression — UCEC

Explore this box plot interactively →