RHBDD1

Across TCGA cell cohorts, RHBDD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,797 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHBDD1-associated GO terms across cancer lineages are ERAD pathway, Regulation of SREBP signaling pathway, and Membrane protein intracellular domain proteolysis. Each is linked with RHBDD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both RHBDD1-to-partner and partner-to-RHBDD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERAD pathway grouped by RHBDD1-low versus RHBDD1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDD1→partner) and Y-score (partner→RHBDD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ERAD pathway →	+0.132	+1.118	<.001	<.001	3	13
PANCREAS	Regulation of SREBP signaling pathway →	+0.082	+0.671	<.001	.003	3	11
BLOOD_Myeloma	Membrane protein intracellular domain proteolysis →	+0.136	+1.237	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.096	-0.643	<.001	.004	2	11
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.096	-0.643	<.001	.004	2	11
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.096	-0.677	<.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,797 associations by consensus.

ERAD pathway by RHBDD1 expression — BLOOD_Myeloma

Explore this box plot interactively →