RGS9

Across TCGA cell cohorts, RGS9 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,331 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RGS9-associated GO terms across cancer lineages are Regulation of calcium ion export across plasma membrane, Cell division, and Mitotic cytokinesis. Each is linked with RGS9 in more than 16 cancer types. Because this analysis shows association rather than direction, both RGS9-to-partner and partner-to-RGS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of calcium ion export across plasma membrane grouped by RGS9-low versus RGS9-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS9→partner) and Y-score (partner→RGS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of calcium ion export across plasma membrane →	-0.114	-1.611	<.001	<.001	3	17
BREAST	Cell division →	+0.097	+1.393	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Mitotic cytokinesis →	+0.102	+2.032	.003	.001	3	9
BREAST	Cytokinesis →	+0.083	+1.361	<.001	<.001	3	9
LUNG_NSCLC_LUSC	ATP synthesis coupled electron transport →	+0.098	+1.768	.001	.001	2	9
LUNG_NSCLC_LUSC	Mitochondrial ATP synthesis coupled electron transport →	+0.098	+1.768	.001	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,331 associations by consensus.

Regulation of calcium ion export across plasma membrane by RGS9 expression — BLOOD_Myeloma

Explore this box plot interactively →