Across TCGA patient cohorts, RGS7BP mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGS7BP-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, MEK1, and STAT3_pY705. Each is linked with RGS7BP in more than 2 cancer types. Because this analysis shows association rather than direction, both RGS7BP-to-partner and partner-to-RGS7BP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS7BP→partner) and Y-score (partner→RGS7BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Acetyl-a-Tubulin-Lys40 →	+0.649	+2.459	.005	.018	3	3
UCEC	MEK1 →	+0.357	+2.459	.030	.019	3	2
UCEC	STAT3_pY705 →	-0.357	-2.000	.002	.032	3	2
UCEC	Caspase-7-cleavedD198 →	+0.778	+3.341	.003	.005	3	2
UCEC	Cyclin-B1 →	+0.608	+2.000	.016	.032	3	2
UCEC	FASN →	+0.675	+3.321	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

RGS7BP survival (RNA) · tumor vs normal (RNA) · all RGS7BP data types