Across TCGA cell cohorts, RGS7BP mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RGS7BP-associated genes across cancer lineages are TGM6, GP2, and FSHB. Each is linked with RGS7BP in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS7BP-to-partner and partner-to-RGS7BP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS7BP→partner) and Y-score (partner→RGS7BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TGM6 →	+0.022	+5.569	<.001	.001	3	1
BLOOD_Leukemia	GP2 →	+0.055	+4.551	<.001	.004	3	1
CNS	FSHB →	+0.025	+5.321	<.001	.005	3	1
LARGE_INTESTINE	PRSS54 →	+0.053	+4.930	<.001	.001	3	1
LARGE_INTESTINE	OR51D1 →	+0.017	+5.217	<.001	<.001	3	1
LARGE_INTESTINE	MROH5 →	+0.144	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

RGS7BP survival (RNA) · tumor vs normal (RNA) · all RGS7BP data types