Across TCGA patient cohorts, RGS6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,024 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS6-associated proteins across cancer lineages are NRBF2, TNKS1BP1_S1073, and ASCC1. Each is linked with RGS6 in more than 3 cancer types. Because this analysis shows association rather than direction, both RGS6-to-partner and partner-to-RGS6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS6→partner) and Y-score (partner→RGS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NRBF2 →	-0.329	-0.187	<.001	.001	3	4
HNSC	TNKS1BP1_S1073 →	-0.469	-0.549	<.001	<.001	3	3
HNSC	ASCC1 →	-0.255	-0.648	<.001	.002	3	3
CCRCC	RPS2 →	-0.258	-0.247	<.001	.003	3	3
BRCA	SYAP1_S313 →	-0.627	-0.427	<.001	.001	3	3
HNSC	CASP4 →	-0.725	-0.844	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,024 associations by consensus.

Exploration

RGS6 survival (RNA) · tumor vs normal (RNA) · all RGS6 data types