RGS6

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RGS6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,853 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RGS6-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Negative regulation of RNA catabolic process, and Cellular response to topologically incorrect protein. Each is linked with RGS6 in more than 6 cancer types. Because this analysis shows association rather than direction, both RGS6-to-partner and partner-to-RGS6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS6→partner) and Y-score (partner→RGS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaRegulation of syncytium formation by plasma membrane fusion →+0.046+0.632.001.00837
OVARYNegative regulation of RNA catabolic process →+0.041+0.464.007.00437
BLOOD_LymphomaCellular response to topologically incorrect protein →+0.044+0.803.003.00536
OVARYNegative regulation of mRNA catabolic process →+0.056+0.560.001<.00136
BREASTDendritic cell differentiation →-0.125-0.605.009.00835
BLOOD_LymphomaLactam metabolic process →-1.478-0.701<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,853 associations by consensus.

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