RGS22

Across TCGA patient cohorts, RGS22 protein abundance is significantly associated with the RNA expression of many other genes, with 1,727 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGS22-associated genes across cancer lineages are GGA1, ANKRD54, and CCDC134. Each is linked with RGS22 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS22-to-partner and partner-to-RGS22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS22 versus GGA1 in LUAD, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS22→partner) and Y-score (partner→RGS22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GGA1 →	-0.557	-0.518	.001	<.001	3	1
LUAD	ANKRD54 →	-0.412	-0.574	.002	<.001	3	1
LUAD	CCDC134 →	-0.387	-0.476	.002	.004	3	1
LUAD	SLC16A8 →	-1.136	-0.785	.002	.004	3	1
LUAD	MYH9 →	-0.580	-0.395	.007	.008	3	1
LUAD	ST13 →	-0.468	-0.630	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,727 associations by consensus.

RGS22 vs GGA1 — LUAD

Explore this scatter interactively →