RGS22

Across TCGA cell cohorts, RGS22 protein abundance is significantly associated with the RNA expression of many other genes, with 2,378 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible RGS22-associated genes across cancer lineages are CHMP4B, MFSD13A, and IFIT1. Each is linked with RGS22 in more than 5 cancer types. Because this analysis shows association rather than direction, both RGS22-to-partner and partner-to-RGS22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS22 versus CHMP4B in LIVER, with a Pearson correlation of 0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS22→partner) and Y-score (partner→RGS22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	CHMP4B →	+1.086	+0.906	.001	.001	3	6
BLOOD_Lymphoma	MFSD13A →	-0.946	-0.959	.005	.008	3	5
OESOPHAGUS	IFIT1 →	+2.631	+0.987	.004	.007	3	4
LUNG_NSCLC_LUSC	MANBAL →	+0.994	+0.998	<.001	.001	3	4
PANCREAS	EDEM2 →	+1.191	+0.909	.005	.009	2	5
SKIN	CD68 →	+1.937	+0.626	.003	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,378 associations by consensus.

RGS22 vs CHMP4B — LIVER

Explore this scatter interactively →