RGS20

Across TCGA patient cohorts, RGS20 protein abundance is significantly associated with the RNA expression of many other genes, with 3,587 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RGS20-associated genes across cancer lineages are CA2, DYRK2, and SLC35D2. Each is linked with RGS20 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS20-to-partner and partner-to-RGS20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS20 versus CA2 in HNSC, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS20→partner) and Y-score (partner→RGS20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CA2 →	+3.027	+2.087	.004	.003	3	2
HNSC	DYRK2 →	-0.785	-1.482	.005	.008	3	2
HNSC	SLC35D2 →	-1.000	-1.977	<.001	.004	3	2
HNSC	NUP210L →	-0.517	-1.390	.001	.006	3	2
HNSC	EML4 →	-1.014	-1.520	.008	.001	3	2
HNSC	ARL13B →	-1.285	-2.002	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,587 associations by consensus.

RGS20 vs CA2 — HNSC

Explore this scatter interactively →