RGS20

Across TCGA cell cohorts, RGS20 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,593 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RGS20-associated GO terms across cancer lineages are Intestinal lipid absorption, Receptor-mediated endocytosis of virus by host cell, and Negative regulation of T-helper cell differentiation. Each is linked with RGS20 in more than 10 cancer types. Because this analysis shows association rather than direction, both RGS20-to-partner and partner-to-RGS20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intestinal lipid absorption grouped by RGS20-low versus RGS20-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS20→partner) and Y-score (partner→RGS20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Intestinal lipid absorption →	+0.268	+1.109	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Receptor-mediated endocytosis of virus by host cell →	+0.345	+2.722	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Negative regulation of T-helper cell differentiation →	+0.150	+1.778	.004	.008	3	9
LUNG_NSCLC_LUSC	Endocytosis involved in viral entry into host cell →	+0.223	+2.360	<.001	<.001	3	9
STOMACH	Negative regulation of type I interferon production →	+0.098	+1.610	.001	.002	3	9
BONE	Uridine metabolic process →	+1.306	+1.283	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,593 associations by consensus.

Intestinal lipid absorption by RGS20 expression — BONE

Explore this box plot interactively →