RGS19

Across TCGA patient cohorts, RGS19 protein abundance is significantly associated with the RNA expression of many other genes, with 17,314 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS19-associated genes across cancer lineages are VNN2, PLEK, and SAMSN1. Each is linked with RGS19 in more than 9 cancer types. Because this analysis shows association rather than direction, both RGS19-to-partner and partner-to-RGS19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS19 versus VNN2 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS19→partner) and Y-score (partner→RGS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VNN2 →	+1.132	+0.436	<.001	<.001	3	10
GBM	PLEK →	+1.083	+0.424	<.001	<.001	3	10
GBM	SAMSN1 →	+1.208	+0.463	<.001	<.001	3	10
GBM	TNFRSF1B →	+1.203	+0.467	<.001	<.001	3	10
GBM	CYTH4 →	+1.020	+0.428	<.001	<.001	3	9
OV	CSF2RB →	+1.308	+0.560	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,314 associations by consensus.

RGS19 vs VNN2 — HNSC

Explore this scatter interactively →