RGS19

Across TCGA patient cohorts, RGS19 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible RGS19-associated genes across cancer lineages are Fibroblasts, Macrophages, and Memory B-cells. Each is linked with RGS19 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS19-to-partner and partner-to-RGS19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fibroblasts grouped by RGS19-low versus RGS19-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS19→partner) and Y-score (partner→RGS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Fibroblasts →	+0.022	+5.797	<.001	.035	3	2
COAD	Macrophages →	+0.019	+4.025	.034	.003	3	2
UCEC	Memory B-cells →	+0.037	+2.903	.026	.032	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Fibroblasts by RGS19 expression — SKCM

Explore this box plot interactively →