RGS19

Across TCGA cell cohorts, RGS19 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RGS19-associated genes across cancer lineages are MMP26 and OR5V1. Each is linked with RGS19 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS19-to-partner and partner-to-RGS19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by RGS19-low versus RGS19-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS19→partner) and Y-score (partner→RGS19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MMP26 →	+0.048	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MMP26 by RGS19 expression — LARGE_INTESTINE

Explore this box plot interactively →