RGS18

Across TCGA patient cohorts, RGS18 protein abundance is significantly associated with the RNA expression of many other genes, with 9,495 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS18-associated genes across cancer lineages are TNFRSF1B, DDX6, and TNFRSF10C. Each is linked with RGS18 in more than 3 cancer types. Because this analysis shows association rather than direction, both RGS18-to-partner and partner-to-RGS18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS18 versus TNFRSF1B in GBM, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS18→partner) and Y-score (partner→RGS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TNFRSF1B →	+1.116	+0.572	<.001	<.001	3	4
HNSC	DDX6 →	-0.638	-0.425	.006	.006	3	3
HNSC	TNFRSF10C →	+1.072	+0.464	.001	.002	3	3
HNSC	FCN1 →	+1.151	+0.549	.003	<.001	3	3
GBM	IL1R1 →	+1.175	+0.507	<.001	<.001	3	3
GBM	IL18R1 →	+0.704	+0.614	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,495 associations by consensus.

RGS18 vs TNFRSF1B — GBM

Explore this scatter interactively →