RGS18

Across TCGA cell cohorts, RGS18 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,341 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RGS18-associated GO terms across cancer lineages are Schwann cell development, Digestive tract development, and Negative regulation of protein modification by small protein conjugation or removal. Each is linked with RGS18 in more than 4 cancer types. Because this analysis shows association rather than direction, both RGS18-to-partner and partner-to-RGS18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Schwann cell development grouped by RGS18-low versus RGS18-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS18→partner) and Y-score (partner→RGS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Schwann cell development →	+0.052	+2.415	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Digestive tract development →	-0.050	-0.052	<.001	.007	3	5
OESOPHAGUS	Negative regulation of protein modification by small protein conjugation or removal →	+0.076	+0.040	.005	.004	3	4
OESOPHAGUS	Negative regulation of protein ubiquitination →	+0.069	+0.039	.004	.006	3	4
BLOOD_Lymphoma	Midgut development →	-0.738	-1.094	.001	.002	3	4
STOMACH	Cytoplasmic translation →	+0.069	+0.055	.005	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,341 associations by consensus.

Schwann cell development by RGS18 expression — BLOOD_Leukemia

Explore this box plot interactively →