RGS17

Across TCGA cell cohorts, RGS17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,687 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RGS17-associated GO terms across cancer lineages are Regulation of telomere capping, Protein localization to lysosome, and Autophagosome assembly. Each is linked with RGS17 in more than 7 cancer types. Because this analysis shows association rather than direction, both RGS17-to-partner and partner-to-RGS17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere capping grouped by RGS17-low versus RGS17-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS17→partner) and Y-score (partner→RGS17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of telomere capping →	+0.077	+0.821	.001	<.001	3	8
LUNG_SCLC	Protein localization to lysosome →	+0.089	+1.785	.002	.001	3	8
BLOOD_Myeloma	Autophagosome assembly →	+0.078	+0.410	.002	.008	3	7
URINARY_TRACT	Positive regulation of excitatory synapse assembly →	-1.403	-1.336	<.001	<.001	3	7
SKIN	Regulation of dense core granule biogenesis →	+0.817	+0.993	<.001	<.001	3	7
CNS	SNARE complex disassembly →	+0.158	+1.308	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

Regulation of telomere capping by RGS17 expression — SKIN

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