RGS16

Across TCGA cell cohorts, RGS16 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RGS16-associated genes across cancer lineages are OR7G2 and CRISP1. Each is linked with RGS16 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS16-to-partner and partner-to-RGS16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7G2 grouped by RGS16-low versus RGS16-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS16→partner) and Y-score (partner→RGS16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR7G2 →	+0.100	+5.285	<.001	.003	3	1
LARGE_INTESTINE	CRISP1 →	+0.019	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR7G2 by RGS16 expression — STOMACH

Explore this box plot interactively →