RGS13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RGS13 mutation is significantly associated with the RNA expression of many other genes, with 99 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGS13-associated genes across cancer lineages are RNA5SP167, RNA5SP198, and RN7SL567P. Each is linked with RGS13 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS13-to-partner and partner-to-RGS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP167 grouped by RGS13-low versus RGS13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS13→partner) and Y-score (partner→RGS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP167 →+0.476+4.245<.001.00632
UCECRNA5SP198 →+0.674+3.399<.001.00532
LUADRN7SL567P →+0.221+4.037.003.00432
BLCACLUHP2 →+0.024+7.640<.001.00932
BLCAHPRT1P2 →+0.059+7.640<.001.00932
UCECNTAN1 →+0.631+3.223.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 99 associations by consensus.

RNA5SP167 by RGS13 expression — UCEC

Box plot of RNA5SP167 in RGS13-low vs RGS13-high samples in UCEC.

Explore this box plot interactively →

Exploration