RGS13

Across TCGA cell cohorts, RGS13 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,032 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RGS13-associated GO terms across cancer lineages are DNA recombination, DNA-templated DNA replication maintenance of fidelity, and Subtelomeric heterochromatin formation. Each is linked with RGS13 in more than 5 cancer types. Because this analysis shows association rather than direction, both RGS13-to-partner and partner-to-RGS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA recombination grouped by RGS13-low versus RGS13-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS13→partner) and Y-score (partner→RGS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA recombination →	+0.076	+0.120	<.001	.006	3	6
OESOPHAGUS	DNA-templated DNA replication maintenance of fidelity →	+0.117	+0.185	.001	.002	3	6
BREAST	Subtelomeric heterochromatin formation →	+0.090	+0.063	.002	.005	3	5
BLOOD_Lymphoma	Centriole-centriole cohesion →	+0.069	+3.660	.001	<.001	3	5
STOMACH	Negative regulation of calcium ion transport into cytosol →	-0.103	-0.157	.002	.001	2	6
BLOOD_Lymphoma	Meiotic cell cycle →	+0.039	+2.812	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,032 associations by consensus.

DNA recombination by RGS13 expression — OESOPHAGUS

Explore this box plot interactively →