RGS10

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RGS10 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,995 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGS10-associated proteins across cancer lineages are ARHGAP45, ARHGAP9, and SAMHD1. Each is linked with RGS10 in more than 6 cancer types. Because this analysis shows association rather than direction, both RGS10-to-partner and partner-to-RGS10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS10 versus ARHGAP45 in GBM, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS10→partner) and Y-score (partner→RGS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMARHGAP45 →+0.594+0.740<.001<.00136
GBMARHGAP9 →+0.510+0.799<.001<.00136
GBMSAMHD1 →+0.443+0.836<.001<.00136
LUADSAMHD1_S33 →+0.783+0.952<.001<.00136
GBMIFI35 →+0.377+0.707<.001<.00136
GBMDEF6 →+0.604+0.919<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,995 associations by consensus.

RGS10 vs ARHGAP45 — GBM

Per-sample scatter of RGS10 vs ARHGAP45 in GBM (Pearson r = 0.67).

Explore this scatter interactively →

Exploration