RGS10

Across TCGA cell cohorts, RGS10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,974 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RGS10-associated GO terms across cancer lineages are Formate biosynthetic process, Negative regulation of stem cell differentiation, and Negative regulation of G protein-coupled receptor signaling pathway. Each is linked with RGS10 in more than 6 cancer types. Because this analysis shows association rather than direction, both RGS10-to-partner and partner-to-RGS10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formate biosynthetic process grouped by RGS10-low versus RGS10-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS10→partner) and Y-score (partner→RGS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Formate biosynthetic process →	+0.123	+1.145	<.001	<.001	3	7
LUNG_SCLC	Negative regulation of stem cell differentiation →	-0.184	-2.546	<.001	<.001	3	7
STOMACH	Negative regulation of G protein-coupled receptor signaling pathway →	+0.078	+1.262	.002	.001	3	7
BLOOD_Leukemia	Neuroendocrine cell differentiation →	+0.267	+1.080	<.001	<.001	3	7
LUNG_NSCLC_LUSC	Cellular response to jasmonic acid stimulus →	-1.766	-1.107	<.001	.005	3	7
LUNG_NSCLC_LUSC	Response to jasmonic acid →	-1.766	-1.107	<.001	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,974 associations by consensus.

Formate biosynthetic process by RGS10 expression — STOMACH

Explore this box plot interactively →