RGR

Across TCGA patient cohorts, RGR protein abundance is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGR-associated genes across cancer lineages are KLK13, FGF20, and C11orf40. Each is linked with RGR in more than 1 cancer types. Because this analysis shows association rather than direction, both RGR-to-partner and partner-to-RGR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGR versus KLK13 in GBM, with a Pearson correlation of 0.82.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGR→partner) and Y-score (partner→RGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KLK13 →	+0.135	+1.183	<.001	.005	3	1
GBM	FGF20 →	+0.623	+0.463	.004	.005	3	1
GBM	C11orf40 →	+0.390	+1.176	.003	.005	2	1
GBM	ALX1 →	+0.280	+0.463	.001	.005	2	1
GBM	OR2A4 →	+0.180	+0.554	.004	.006	2	1
GBM	SNAI2 →	-0.913	-0.423	.009	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

RGR vs KLK13 — GBM

Explore this scatter interactively →