RGR

Across TCGA cell cohorts, RGR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,994 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RGR-associated GO terms across cancer lineages are Negative regulation of cell activation, Hormone transport, and Vascular process in circulatory system. Each is linked with RGR in more than 4 cancer types. Because this analysis shows association rather than direction, both RGR-to-partner and partner-to-RGR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell activation grouped by RGR-low versus RGR-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGR→partner) and Y-score (partner→RGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of cell activation →	-0.078	-0.051	<.001	.005	3	5
SOFT_TISSUE	Hormone transport →	-0.068	-0.654	.004	.003	3	5
SOFT_TISSUE	Vascular process in circulatory system →	-0.034	-0.882	.003	.004	3	5
LUNG_NSCLC_LUSC	Negative regulation of tumor necrosis factor superfamily cytokine production →	-0.129	-0.032	<.001	.008	3	4
LUNG_NSCLC_LUSC	Antigen processing and presentation →	-0.142	-0.048	.001	.007	3	4
LUNG_NSCLC_LUSC	Regulation of interleukin-6 production →	-0.065	-0.044	.005	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,994 associations by consensus.

Negative regulation of cell activation by RGR expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →