RGPD3

Across TCGA cell cohorts, RGPD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,911 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RGPD3-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Heterochromatin formation, and Heterochromatin organization. Each is linked with RGPD3 in more than 11 cancer types. Because this analysis shows association rather than direction, both RGPD3-to-partner and partner-to-RGPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by RGPD3-low versus RGPD3-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD3→partner) and Y-score (partner→RGPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of organelle assembly →	+0.055	+0.884	<.001	.004	3	12
LARGE_INTESTINE	Heterochromatin formation →	+0.065	+0.209	<.001	<.001	3	10
STOMACH	Heterochromatin organization →	+0.077	+0.198	.002	.002	1	11
OESOPHAGUS	Termination of RNA polymerase II transcription →	+0.117	+0.082	.006	.004	3	9
LUNG_SCLC	Regulation of microtubule-based process →	+0.082	+0.226	<.001	.002	2	10
OVARY	Golgi organization →	+0.050	+0.119	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,911 associations by consensus.

Positive regulation of organelle assembly by RGPD3 expression — BLOOD_Leukemia

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