RGPD3

Across TCGA cell cohorts, RGPD3 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RGPD3-associated genes across cancer lineages are PAK5, TCF21, and PAX1. Each is linked with RGPD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGPD3-to-partner and partner-to-RGPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PAK5 grouped by RGPD3-low versus RGPD3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD3→partner) and Y-score (partner→RGPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PAK5 →	+0.115	+4.234	<.001	.003	3	1
BLOOD_Leukemia	TCF21 →	+0.008	+3.705	.002	.007	3	1
BLOOD_Leukemia	PAX1 →	+0.046	+4.060	<.001	.003	3	1
BLOOD_Leukemia	GH2 →	+0.017	+4.384	<.001	.006	3	1
BLOOD_Leukemia	FRMPD4 →	+0.728	+4.037	<.001	.004	3	1
BLOOD_Leukemia	OR9G1 →	+0.230	+3.874	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

PAK5 by RGPD3 expression — BLOOD_Leukemia

Explore this box plot interactively →