Across TCGA patient cohorts, RGPD2 mutation is significantly associated with the RNA expression of many other genes, with 353 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGPD2-associated genes across cancer lineages are MTATP6P30, MRPS11P1, and MTATP6P21. Each is linked with RGPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGPD2-to-partner and partner-to-RGPD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD2→partner) and Y-score (partner→RGPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MTATP6P30 →	+0.309	+7.731	<.001	.009	3	2
UCEC	MRPS11P1 →	+0.144	+2.813	<.001	.003	3	2
UCEC	MTATP6P21 →	+0.417	+2.704	<.001	.004	3	2
UCEC	VN1R69P →	+0.129	+3.274	<.001	.001	3	2
BRCA	MIR6853 →	+0.364	+9.057	<.001	.003	3	1
BRCA	MIR6507 →	+1.306	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 353 associations by consensus.

Exploration

RGPD2 survival (RNA) · tumor vs normal (RNA) · all RGPD2 data types