RGPD2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RGPD2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGPD2-associated genes across cancer lineages are PDCD4, Tuberin, and VEGFR2. Each is linked with RGPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGPD2-to-partner and partner-to-RGPD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD2→partner) and Y-score (partner→RGPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPDCD4 →-0.946-3.000<.001.03731
UCECTuberin →+0.350+3.000.024.03731
UCECVEGFR2 →+0.356+3.013.038.01931
UCECRad50 →-0.349-3.000.012.03721
UCECERK2 →+0.247+3.000.026.03711
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration