Across TCGA cell cohorts, RGPD2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RGPD2-associated genes across cancer lineages are OR10T2, SLC22A12, and OR10R2. Each is linked with RGPD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGPD2-to-partner and partner-to-RGPD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGPD2→partner) and Y-score (partner→RGPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10T2 →	+0.699	+4.276	<.001	.007	3	1
BLOOD_Leukemia	SLC22A12 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR10R2 →	+2.472	+4.551	<.001	.004	3	1
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

RGPD2 survival (RNA) · tumor vs normal (RNA) · all RGPD2 data types