RGMB

Across TCGA patient cohorts, RGMB protein abundance is significantly associated with the RNA expression of many other genes, with 6,265 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGMB-associated genes across cancer lineages are WDPCP, GRIK2, and BBS10. Each is linked with RGMB in more than 2 cancer types. Because this analysis shows association rather than direction, both RGMB-to-partner and partner-to-RGMB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGMB versus WDPCP in BRCA, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGMB→partner) and Y-score (partner→RGMB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDPCP →	+0.534	+0.780	<.001	<.001	3	3
GBM	GRIK2 →	+1.108	+0.533	<.001	<.001	3	3
BRCA	BBS10 →	+0.920	+0.780	.001	<.001	3	3
BRCA	CNTN1 →	+1.920	+0.780	.006	<.001	3	3
UCEC	GUCY1B2 →	+1.133	+1.118	.005	.001	3	2
UCEC	CIITA →	-0.710	-0.825	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,265 associations by consensus.

RGMB vs WDPCP — BRCA

Explore this scatter interactively →