RGMB

Across TCGA cell cohorts, RGMB RNA expression is significantly associated with the go_rna of many other GO terms, with 5,125 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RGMB-associated GO terms across cancer lineages are Positive regulation of pinocytosis, Regulation of protein localization to early endosome, and Positive regulation of protein localization to early endosome. Each is linked with RGMB in more than 10 cancer types. Because this analysis shows association rather than direction, both RGMB-to-partner and partner-to-RGMB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of pinocytosis grouped by RGMB-low versus RGMB-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGMB→partner) and Y-score (partner→RGMB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of pinocytosis →	+0.136	+2.004	<.001	<.001	3	11
BONE	Regulation of protein localization to early endosome →	+0.107	+1.394	.001	.002	3	10
BONE	Positive regulation of protein localization to early endosome →	+0.107	+1.394	.001	.002	3	10
BONE	Positive regulation of ferroptosis →	+0.151	+1.981	<.001	<.001	3	10
BONE	Neuropilin signaling pathway →	+0.203	+1.944	<.001	<.001	3	10
LARGE_INTESTINE	Positive regulation of NK T cell proliferation →	-1.251	-2.034	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,125 associations by consensus.

Positive regulation of pinocytosis by RGMB expression — LUNG_NSCLC_LUSC

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