RGL2

Across TCGA patient cohorts, RGL2 mutation is significantly associated with the RNA expression of many other genes, with 2,010 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGL2-associated genes across cancer lineages are RNY1P1, FBXO36P1, and RPS29P32. Each is linked with RGL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RGL2-to-partner and partner-to-RGL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY1P1 grouped by RGL2-low versus RGL2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGL2→partner) and Y-score (partner→RGL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNY1P1 →	+0.153	+4.342	<.001	.007	3	3
COAD	FBXO36P1 →	+0.360	+3.298	<.001	.001	3	3
UCEC	RPS29P32 →	+0.347	+2.014	<.001	.001	3	3
HNSC	RNU6-1114P →	+0.263	+3.597	.004	.007	3	2
SKCM	YPEL5P3 →	+0.080	+4.797	<.001	.003	3	2
SKCM	LARP7P3 →	+0.400	+4.199	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,010 associations by consensus.

RNY1P1 by RGL2 expression — CESC

Explore this box plot interactively →